Factors influencing temporal variation of scrapie incidence within a closed Suffolk sheep flock
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چکیده
منابع مشابه
Scrapie epidemic in a fully PrP-genotyped sheep flock.
In scrapie-affected sheep flocks, host PrP genotype plays a vital role in determining which sheep will succumb to scrapie and the incubation period. Consequently, within-flock scrapie dynamics is best understood within the context of the genotype profile of the flock. Here we describe a 17 month epidemic of scrapie in a commercially farmed flock of 230 genotyped Texel sheep. At the start of the...
متن کاملAtypical scrapie in sheep from a UK research flock which is free from classical scrapie
BACKGROUND In the wake of the epidemic of bovine spongiform encephalopathy the British government established a flock of sheep from which scrapie-free animals are supplied to laboratories for research. Three breeds of sheep carrying a variety of different genotypes associated with scrapie susceptibility/resistance were imported in 1998 and 2001 from New Zealand, a country regarded as free from ...
متن کاملDevelopment of Anthelmintic Resistance in a Closed Sheep Flock
Changes in anthelmintic resistance over the past 16 years is documented following the isolation of a field strain of Haemonchus contortus in sheep showing multiple anthelmintic resistance at Lawes in south eastern Queensland in 1979. Resistance to thiabendazole was first suspected in 1969 and continued to persist until the present time. In addition resistance to fenbendazole and oxfendazole als...
متن کاملPolygenic variation and transmission factors involved in the resistance/susceptibility to scrapie in a Romanov flock.
Data from 4049 Romanov sheep belonging to a flock affected by natural scrapie were analysed by using survival-analysis techniques. Failure time was defined as the period of time between first exposure to infection and the date that animals left the flock with scrapie signs. Four hundred and forty-seven sheep were identified as 'scrapie animals'. Several models, including level of exposure as a ...
متن کاملDynamics of a scrapie outbreak in a flock of Romanov sheep--estimation of transmission parameters.
Knowledge of epidemiological mechanisms and parameters underlying scrapie transmission in sheep flocks remains very limited at present. Here we introduce a method for fitting stochastic transmission models to outbreak data to estimate bounds on key transmission parameters. We apply this method to data describing an outbreak of scrapie in a closed flock of Romanov sheep. The main findings are th...
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ژورنال
عنوان ژورنال: Journal of General Virology
سال: 2012
ISSN: 0022-1317,1465-2099
DOI: 10.1099/vir.0.034652-0